A deal dies not from a “no” but from silence, a forgotten address and a contact who moved on.

Catalyst finds new clients for a CRO and brings back old ones — it spots the reason to write, drafts the email in the rep’s voice and hands it over for approval.

By default, no email goes out until the rep taps “send”; auto mode is switched on by you, where accuracy is proven.

Who this is for

A CRO — medicinal chemistry, screening, biology, DMPK, preclinical or clinical services — whose new business is a few high-value contracts with pharma and biotech, won through people rather than advertising. You own the pipeline. You approve every email. Your mailbox, CRM and LinkedIn stay yours.

Design partners, not a waiting list.

We work with a small number of CRO and CDMO teams at a time — each shapes the platform and runs it first.

42,966

new clinical studies registered in 2025

ClinicalTrials.gov · by first-posted date · counted 13 September 2026

62,804

NIH-funded projects in fiscal year 2025

NIH RePORTER · NIH only, sub-projects excluded · counted 13 September 2026

46

novel drugs approved by the FDA in 2025

FDA Center for Drug Evaluation and Research · Novel Drug Approvals for 2025 · checked 13 September 2026

Research outsourced to CROs — $69.6–85.4 billion in 2025. Development and manufacturing outsourced to CDMOs — $197.4–258.9 billion.

published estimates for 2025: Precedence Research (Feb–Mar 2026), MarketsandMarkets (Apr 2026), Mordor Intelligence (Sep 2026)

What you get

A reason to write today, a draft in your rep’s voice, one tap.

01

The rep decides — the system carries out

Every draft waits in the rep’s workspace until a human taps “send” or “skip”.

02

A reply becomes a deal

The moment a lead answers, a deal opens in your CRM with owner, stage and value.

03

Follow-ups continue without a reminder

Nobody disappears in silence — the next touch is drafted and ready when it is due.

66

replies classified as positive

from one client’s pipeline, not a forecast · measured 17 September 2026

How it works — one loop

  1. Signal
  2. Email
  3. Reply
  1. 01 · Signal

    A public event points to a company, then a person.

    A grant, a funding round, a clinical trial — each means new budget or new work. The signal points to the company, the company to the right person in the right role: chief scientific, executive or business officer. The address is verified before anything is written.

    Signal → person → email → reply → deal — and back01 / 03

    Signals of new budget and new work

    • Research funding
    • Financing rounds
    • Clinical milestones
    • Regulatory decisions
    • Patents and publications
    • Hiring for new programs

    Company → person

    • from the company name to its domain
    • the right role: chief scientific, executive or business officer
    • address verified
  2. 02 · Email

    A draft in the rep’s voice, from approved facts only.

    The draft arrives as a card with the trigger and any warnings. One tap — send, skip, mark bad text, or take the contact. It goes from the rep’s own mailbox, in the same thread. No line is invented; the draft rests on approved facts only.

    Signal → person → email → reply → deal — and back02 / 03

    The card

    • the email itself
    • the trigger
    • warnings: “we owe this lead a reply”, “this is Big Pharma”
    • four buttons: send · skip · bad text · take the contact

    From the rep’s own mailbox

    • in the same thread
    • signature, title, postal address, unsubscribe line — or no email
    • approved facts only
  3. 03 · Reply

    Every reply is read, classified and given an action.

    Interested — the rep is alerted. “Not now” — a pause with a date, and the lead returns on its own. “Talk to my colleague” — the conversation moves. Unsubscribe — the contact joins the do-not-contact list. A reply becomes a deal in the CRM.

    Signal → person → email → reply → deal — and back03 / 03

    Reply → its action

    • interested → the rep is alerted
    • “not now” → a pause with a date
    • “talk to my colleague” → the conversation moves
    • unsubscribe → do-not-contact list

    Deal in the CRM

    • owner
    • stage
    • value

    no reply — the next email in the sequence, on schedule; sooner with a new signal

Five engines — one system

Three channels — email, LinkedIn and SMS — never at once with one person; SMS only for key contacts, by an approved card.

01RADAR

reads public signals and turns an event into a lead.

02Reactivation

a short sequence that reopens quiet deals, no repeats.

03Cold outreach

first contact with people you have not met, under its own daily cap.

04Auto mode

sends without a tap only where accuracy is proven.

05Sprint

conferences and trips: the calendar fills before the rep packs. Two modes — conference or trip. People return to the usual engines afterwards.

One email, end to end

What the rep sees — and what happens after one tap.

A fictional example: the company, the people and the email are invented; the card is what the rep sees in the workspace.

TriggerYesterday: a grant announced for a lead-compound program at a biotech — public registry entry
ToDr. Lena Hart, Chief Scientific Officer, Arbor Therapeutics (fictional)
Checksaddress verifiedno live conversation at this companynot Big Pharmawithin this week’s sending cap
SubjectCongratulations on the grant — DMPK capacity when the program needs it

Dr. Hart — congratulations on the grant for your lead-compound program announced yesterday.

When a program moves from hit to lead, DMPK and in vivo PK studies usually become the bottleneck; we run exactly these studies for early-stage biotech teams.

If useful, I can send a one-page outline of what a first study looks like and typical timing.

Would a short call next week suit you?

Anna Lewis · Head of Business Development · Northline Research (fictional) · postal address · unsubscribe

Four buttonssendskipbad texttake the contact
After the tap
  • sent from Anna’s own mailbox — a new thread, because there was none yet
  • reply: “Timing is right — can we talk on Tuesday?”
  • classified as interested → Anna is alerted
  • meeting → a deal in the CRM: owner, stage, value

Every reply gets an action

The rep only sees what needs a human; pauses, do-not-contact entries and return dates happen on their own.

01

Agreed to a meeting

names a time, books or gives a phone number → alert the rep immediately

02

Interested, nothing specific

“sounds good”, “I’ll check my calendar” → the sequence pauses, the decision is the human’s

03

To a colleague

“talk to X” → contact swap

04

“Not now” or budget frozen

→ a pause with a date; the lead comes back on its own

05

Decline

“not relevant for us”, “we’re covered” → stop and do-not-contact

06

Question about services or price

→ straight to the rep

07

Left the company

→ a search for the successor in the same role

08

Project closed or went elsewhere

→ the reason for the loss is recorded

The rep stays in control

Approval card

carries the trigger and any warnings before you decide.

One tap

send, skip, mark bad text, or take the contact.

Caps and one list

sending is capped over a rolling week, and one do-not-contact list covers every engine.

One key

pauses outgoing email.

Your team, your data

Your accounts stay yours — the boundary is enforced by the database.

Your rep sends, from their own mailbox

in the same thread; nothing goes out from a shared Kason address, and each client sends only from its own accounts

Isolation by the database itself

every record is tied to your workspace, and isolation tests try exactly that — one client reading another’s data — and must fail

Hosted in the European Union

your database is hosted in an EU region, where the provider stores and primarily processes it; providers are listed by category on the subprocessors page

A full export at any time

in a standard database format — ask us and we will deliver it; when someone leaves your team, their leads are handed over along a documented path

No footer, no email

the gates require a signature, a title, the company’s postal address and an unsubscribe line

Address check before every email

external deliverability verification: an address that fails the check gets no email, so far fewer bounces reach your domain

1.3×

failure-handling steps for every working step

For every working step there are 1.3 steps that handle failure — more for failure than for the work itself

measured in September 2026 · how data is handled

Two ways to run it

Format A — our business development manager runs the engines and takes leads to the call, inside your accounts and in your rep’s voice. Format B — your team runs it day to day, and we support the setup and the rules. Both keep the same control: the rep approves every email, and your accounts stay yours.

Subscription pricing is discussed on the first call.

The questions a buyer asks first

Short answers about your data; the full terms will go into the data processing agreement each client signs with us.

01Whose data is it?

Yours. Every lead, email, note and reply belongs to your workspace. You can have a full export at any time in a standard database format — ask us and we will deliver it.

02Can another client see our leads?

The database itself enforces the boundary, not only the app: every record is tied to your workspace, and isolation tests try exactly that — one client reading another’s data.

03Where is the data stored?

Your database is hosted in a European Union region, where the provider stores and primarily processes it. Providers that process your data are listed by category on the subprocessors page; clients receive the named list and advance notice of changes under the data processing agreement.

04Who sends the emails?

Your rep, from their own mailbox, in the same thread. Nothing goes out from a shared Kason address, and each client sends only from its own accounts.

05What happens when we leave?

You take a full export of your data. And when someone leaves your team, their leads are handed over along a documented path — nothing is lost in a chat.

06Someone asked to be erased — then what?

The system recognizes the request on its own and raises an alarm well before the legal deadline. The erasure is completed within the legal deadline; only a minimal record of the refusal is kept, so the address is not written to again.

07Can we pause all outgoing email at once?

Yes — one key pauses Catalyst’s outgoing email, and sending is capped over a rolling week.

Design partners, not a waiting list.

We work with a small number of CRO and CDMO teams at a time — each shapes the platform and runs it first. Run it yourself, or have us run it for you.

Security · how data is handled · subprocessors · privacy

Catalyst · five engines: RADAR · reactivation + follow-ups · cold outreach · auto mode · sprint

your CRM and your reps’ mailboxes stay yours · your data can be exported in full at any time